USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: GBB2_HUMAN USC-OGP 2-DE database:  GBB2_HUMAN GBB2_HUMAN General information about the entry View entry in simple text format Entry name GBB2_HUMAN Primary accession number P62879 Secondary accession number(s) P11016 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2; AltName: Full=G protein subunit beta-2; AltName: Full=Transducin beta chain 2;. Gene name Name=GNB2 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0457: pI=5.34; Mw=34480 SPOT OGP-0459: pI=5.23; Mw=34396 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0738: pI=5.21; Mw=35517 SPOT OGP-0743: pI=5.23; Mw=34991 Cross-references UniProtKB/Swiss-Prot P62879; GBB2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name GBB2_HUMAN Primary accession number P62879 Secondary accession number(s) B3KPU1 P11016 P54312 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  March 15, 2017 (version 143) Name and origin of the protein Description RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2; AltName: Full=G protein subunit beta-2; AltName: Full=Transducin beta chain 2; Gene name Name=GNB2 Encoded on Name=GNB2 Keywords Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Reference proteome; Repeat; Transducer; WD repeat. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M16514; AAA03179.1; -; mRNA EMBL M36429; AAA63264.1; -; mRNA EMBL M16538; AAA35922.1; -; mRNA EMBL AF053356; AAC78794.1; -; Genomic_DNA EMBL AF501883; AAM15919.1; -; mRNA EMBL AK056750; BAG51803.1; -; mRNA EMBL AC009488; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC010073; AAH10073.1; -; mRNA EMBL BC012348; AAH12348.1; -; mRNA EMBL BC068003; AAH68003.1; -; mRNA CCDS CCDS5703.1; -. [P62879-1]; . PIR B26617; RGHUB2; . RefSeq NP_005264.2; NM_005273.3. [P62879-1]; . UniGene Hs.185172; -; . ProteinModelPortal P62879; -; . SMR P62879; -; . BioGrid 109045; 158; . IntAct P62879; 45; . MINT MINT-1139073; -; . STRING 9606.ENSP00000305260; -; . iPTMnet P62879; -; . PhosphoSitePlus P62879; -; . SwissPalm P62879; -; . BioMuta GNB2; -; . DMDM 51317304; -; . OGP P62879; -; . REPRODUCTION-2DPAGE P62879; -; . EPD P62879; -; . PaxDb P62879; -; . PeptideAtlas P62879; -; . PRIDE P62879; -; . TopDownProteomics P62879-1; -. [P62879-1]; . DNASU 2783; -; . Ensembl ENST00000303210; ENSP00000305260; ENSG00000172354. [P62879-1]; . Ensembl ENST00000393924; ENSP00000377501; ENSG00000172354. [P62879-1]; . Ensembl ENST00000393926; ENSP00000377503; ENSG00000172354. [P62879-1]; . Ensembl ENST00000419828; ENSP00000390543; ENSG00000172354. [P62879-2]; . Ensembl ENST00000427895; ENSP00000400286; ENSG00000172354. [P62879-2]; . GeneID 2783; -; . KEGG hsa:2783; -; . UCSC uc064ggx.1; human. [P62879-1]; . CTD 2783; -; . GeneCards GNB2; -; . HGNC HGNC:4398; GNB2; . HPA CAB010032; -; . HPA HPA040736; -; . MIM 139390; gene; . neXtProt NX_P62879; -; . OpenTargets ENSG00000172354; -; . PharmGKB PA28778; -; . eggNOG KOG0286; Eukaryota; . eggNOG ENOG410XQUX; LUCA; . GeneTree ENSGT00760000119239; -; . HOGENOM HOG000176356; -; . HOVERGEN HBG000188; -; . InParanoid P62879; -; . KO K04537; -; . OMA EPVCGIT; -; . OrthoDB EOG091G0A7T; -; . PhylomeDB P62879; -; . TreeFam TF106149; -; . Reactome R-HSA-1296041; Activation of G protein gated Potassium channels; . Reactome R-HSA-163359; Glucagon signaling in metabolic regulation; . Reactome R-HSA-202040; G-protein activation; . Reactome R-HSA-381676; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; . Reactome R-HSA-392170; ADP signalling through P2Y purinoceptor 12; . Reactome R-HSA-392451; G beta:gamma signalling through PI3Kgamma; . Reactome R-HSA-392851; Prostacyclin signalling through prostacyclin receptor; . Reactome R-HSA-400042; Adrenaline; noradrenaline inhibits insulin secretion; . Reactome R-HSA-4086398; Ca2+ pathway; . Reactome R-HSA-416476; G alpha (q) signalling events; . Reactome R-HSA-416482; G alpha (12/13) signalling events; . Reactome R-HSA-418217; G beta:gamma signalling through PLC beta; . Reactome R-HSA-418555; G alpha (s) signalling events; . Reactome R-HSA-418592; ADP signalling through P2Y purinoceptor 1; . Reactome R-HSA-418594; G alpha (i) signalling events; . Reactome R-HSA-418597; G alpha (z) signalling events; . Reactome R-HSA-420092; Glucagon-type ligand receptors; . Reactome R-HSA-428930; Thromboxane signalling through TP receptor; . Reactome R-HSA-432040; Vasopressin regulates renal water homeostasis via Aquaporins; . Reactome R-HSA-456926; Thrombin signalling through proteinase activated receptors (PARs); . Reactome R-HSA-500657; Presynaptic function of Kainate receptors; . Reactome R-HSA-6814122; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; . Reactome R-HSA-997272; Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits; . SignaLink P62879; -; . SIGNOR P62879; -; . ChiTaRS GNB2; human; . GeneWiki GNB2; -; . GenomeRNAi 2783; -; . PRO PR:P62879; -; . Proteomes UP000005640; Chromosome 7; . Bgee ENSG00000172354; -; . CleanEx HS_GNB2; -; . ExpressionAtlas P62879; baseline and differential; . Genevisible P62879; HS; . GO GO:0044297; C:cell body; IEA:Ensembl; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005615; C:extracellular space; IDA:UniProtKB; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0005765; C:lysosomal membrane; IDA:UniProtKB; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0043209; C:myelin sheath; IEA:Ensembl; . GO GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB; . GO GO:0005886; C:plasma membrane; TAS:Reactome; . GO GO:0043234; C:protein complex; IEA:Ensembl; . GO GO:0031982; C:vesicle; IDA:UniProtKB; . GO GO:0005246; F:calcium channel regulator activity; IEA:Ensembl; . GO GO:0003924; F:GTPase activity; TAS:ProtInc; . GO GO:0051020; F:GTPase binding; IPI:UniProtKB; . GO GO:0032403; F:protein complex binding; IDA:MGI; . GO GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW; . GO GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome; . GO GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc; . GO GO:0006457; P:protein folding; TAS:Reactome; . Gene3D 2.130.10.10; -; 1; . InterPro IPR020472; G-protein_beta_WD-40_rep; . InterPro IPR001632; Gprotein_B; . InterPro IPR016346; Guanine_nucleotide-bd_bsu; . InterPro IPR015943; WD40/YVTN_repeat-like_dom; . InterPro IPR001680; WD40_repeat; . InterPro IPR019775; WD40_repeat_CS; . InterPro IPR017986; WD40_repeat_dom; . PANTHER PTHR19850; PTHR19850; 1; . Pfam PF00400; WD40; 7; . PRINTS PR00319; GPROTEINB; . PRINTS PR00320; GPROTEINBRPT; . SMART SM00320; WD40; 7; . SUPFAM SSF50978; SSF50978; 1; . PROSITE PS00678; WD_REPEATS_1; 3; . PROSITE PS50082; WD_REPEATS_2; 6; . PROSITE PS50294; WD_REPEATS_REGION; 1; .

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